Polyposis Coli,Familial

《英文msh词典》Polyposis Coli,Familial
[同义词] Polyposis Coli,Familial
[主题词] Adenomatous Polyposis Coli
[中文释义] 息肉病,家族性结肠
[英文释义] A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES,APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood. The lifetime risk of colorectal cancer in these patients reaches 100 percent by age 60.